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The AHA also recommends at least 150 minutes of moderate exercise a week for heart health. Weight loss and maintenance might take a lot more exercise than that, Carson said, which could be a problem for those on ketogenic diets. "Another overall issue is that when you're following a ketogenic diet, you're probably not eating as much regular fruits and vegetables as a heart-healthy diet pattern would have," Carson said. "Depending on your approach, can contribute to significant lean body mass loss along with fat loss," said Melinda Manore, a professor of nutrition at Oregon State University.

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